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The Amyloidogenic V122I Transthyretin Variant in Elderly Black Americans

The Amyloidogenic V122I Transthyretin Variant in Elderly Black Americans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4382209

The Amyloidogenic V122I Transthyretin Variant in Elderly Black Americans

About this item

Full title

The Amyloidogenic V122I Transthyretin Variant in Elderly Black Americans

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2015-01, Vol.372 (1), p.21-29

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

In a cohort study, 3856 black Americans were genotyped for the amyloidogenic V122I transthyretin variant; 124 were variant carriers. At a median follow-up of 21.5 years, carriers did not differ significantly from noncarriers in mortality but had a higher risk of incident heart failure.
Amyloid heart disease leads to an increase in ventricular wa...

Alternative Titles

Full title

The Amyloidogenic V122I Transthyretin Variant in Elderly Black Americans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4382209

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4382209

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1404852

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