Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer e...
Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution
About this item
Full title
Author / Creator
Kovac, Michal , Navas, Carolina , Horswell, Stuart , Salm, Max , Bardella, Chiara , Rowan, Andrew , Stares, Mark , Castro-Giner, Francesc , Fisher, Rosalie , de Bruin, Elza C. , Kovacova, Monika , Gorman, Maggie , Makino, Seiko , Williams, Jennet , Jaeger, Emma , Jones, Angela , Howarth, Kimberley , Larkin, James , Pickering, Lisa , Gore, Martin , Nicol, David L. , Hazell, Steven , Stamp, Gordon , O’Brien, Tim , Challacombe, Ben , Matthews, Nik , Phillimore, Benjamin , Begum, Sharmin , Rabinowitz, Adam , Varela, Ignacio , Chandra, Ashish , Horsfield, Catherine , Polson, Alexander , Tran, Maxine , Bhatt, Rupesh , Terracciano, Luigi , Eppenberger-Castori, Serenella , Protheroe, Andrew , Maher, Eamonn , El Bahrawy, Mona , Fleming, Stewart , Ratcliffe, Peter , Heinimann, Karl , Swanton, Charles and Tomlinson, Ian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Papillary renal cell carcinoma (pRCC) is an important subtype of kidney cancer with a problematic pathological classification and highly variable clinical behaviour. Here we sequence the genomes or exomes of 31 pRCCs, and in four tumours, multi-region sequencing is undertaken. We identify
BAP1
,
SETD2
,
ARID2
and Nrf2 pathway gene...
Alternative Titles
Full title
Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution
Authors, Artists and Contributors
Author / Creator
Navas, Carolina
Horswell, Stuart
Salm, Max
Bardella, Chiara
Rowan, Andrew
Stares, Mark
Castro-Giner, Francesc
Fisher, Rosalie
de Bruin, Elza C.
Kovacova, Monika
Gorman, Maggie
Makino, Seiko
Williams, Jennet
Jaeger, Emma
Jones, Angela
Howarth, Kimberley
Larkin, James
Pickering, Lisa
Gore, Martin
Nicol, David L.
Hazell, Steven
Stamp, Gordon
O’Brien, Tim
Challacombe, Ben
Matthews, Nik
Phillimore, Benjamin
Begum, Sharmin
Rabinowitz, Adam
Varela, Ignacio
Chandra, Ashish
Horsfield, Catherine
Polson, Alexander
Tran, Maxine
Bhatt, Rupesh
Terracciano, Luigi
Eppenberger-Castori, Serenella
Protheroe, Andrew
Maher, Eamonn
El Bahrawy, Mona
Fleming, Stewart
Ratcliffe, Peter
Heinimann, Karl
Swanton, Charles
Tomlinson, Ian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383019
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7336
