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Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell...

Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383027

Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures

About this item

Full title

Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures

Publisher

Athens: D.A. Spandidos

Journal title

International journal of oncology, 2015-05, Vol.46 (5), p.1913-1923

Language

English

Formats

Publication information

Publisher

Athens: D.A. Spandidos

More information

Scope and Contents

Contents

Epithelial-to-mesenchymal transition (EMT) confers stem cell-like phenotype and more motile properties to carcinoma cells. During EMT, the expression of E-cadherin decreases, resulting in loss of cell-cell adhesion and increased migration. Expression of Twist1 and other pleiotropic transcription factors, such as Snail, is known to activate EMT. We...

Alternative Titles

Full title

Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383027

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383027

Other Identifiers

ISSN

1019-6439

E-ISSN

1791-2423

DOI

10.3892/ijo.2015.2911

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