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Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase...

Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4385940

Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6

About this item

Full title

Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2015-03, Vol.6 (3), p.e1691-e1691

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Although numerous pathogenic changes within the mitochondrial respiratory chain (RC) have been associated with an elevated occurrence of apoptosis within the affected tissues, the mechanistic insight into how mitochondrial dysfunction initiates apoptotic cell death is still unknown. In this study, we show that the specific alteration of the cytochr...

Alternative Titles

Full title

Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4385940

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4385940

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/cddis.2015.62

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