Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase...
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
About this item
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Author / Creator
Schüll, S , Günther, S D , Brodesser, S , Seeger, J M , Tosetti, B , Wiegmann, K , Pongratz, C , Diaz, F , Witt, A , Andree, M , Brinkmann, K , Krönke, M , Wiesner, R J and Kashkar, H
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Although numerous pathogenic changes within the mitochondrial respiratory chain (RC) have been associated with an elevated occurrence of apoptosis within the affected tissues, the mechanistic insight into how mitochondrial dysfunction initiates apoptotic cell death is still unknown. In this study, we show that the specific alteration of the cytochr...
Alternative Titles
Full title
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4385940
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4385940
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2015.62