TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
About this item
Full title
Author / Creator
Wu, Haibo , Wang, Yongsheng , Zhang, Yan , Yang, Mingqi , Lv, Jiaxing , Liu, Jun and Zhang, Yong
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Transcription activator-like effector nuclease (TALEN)-mediated genome modification has been applied successfully to create transgenic animals in various species, such as mouse, pig, and even monkey. However, transgenic cattle with gene knockin have yet to be created using TALENs. Here, we report site-specific knockin of the transcription activator...
Alternative Titles
Full title
TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4386332
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4386332
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1421587112
