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Heparanase activates the syndecan-syntenin-ALIX exosome pathway

Heparanase activates the syndecan-syntenin-ALIX exosome pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4387558

Heparanase activates the syndecan-syntenin-ALIX exosome pathway

About this item

Full title

Heparanase activates the syndecan-syntenin-ALIX exosome pathway

Publisher

London: Nature Publishing Group UK

Journal title

Cell research, 2015-04, Vol.25 (4), p.412-428

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Exosomes are secreted vesicles of endosomal origin involved in signaling processes. We recently showed that the syndecan heparan sulfate proteoglycans control the biogenesis of exosomes through their interaction with synten- in-1 and the endosomai-sorting complex required for transport accessory component ALIX. Here we investigated the role of hepa...

Alternative Titles

Full title

Heparanase activates the syndecan-syntenin-ALIX exosome pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4387558

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4387558

Other Identifiers

ISSN

1001-0602

E-ISSN

1748-7838

DOI

10.1038/cr.2015.29

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