Heparanase activates the syndecan-syntenin-ALIX exosome pathway
Heparanase activates the syndecan-syntenin-ALIX exosome pathway
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Exosomes are secreted vesicles of endosomal origin involved in signaling processes. We recently showed that the syndecan heparan sulfate proteoglycans control the biogenesis of exosomes through their interaction with synten- in-1 and the endosomai-sorting complex required for transport accessory component ALIX. Here we investigated the role of hepa...
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Heparanase activates the syndecan-syntenin-ALIX exosome pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4387558
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4387558
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2015.29