Synergistic induction of CCL2/MCP‐1 expression driven by oncostatin M and IL‐1β in human proximal tu...
Synergistic induction of CCL2/MCP‐1 expression driven by oncostatin M and IL‐1β in human proximal tubular cells depends on STAT3 and p65 NFκB/RelA
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Publisher
United States: BlackWell Publishing Ltd
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Language
English
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Publisher
United States: BlackWell Publishing Ltd
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Contents
In response to tubular injury, production, and secretion of cytokines, chemokines or extracellular matrix components by human proximal tubular epithelial cells (PTC) directly contribute to the development of tubulointerstitial inflammation and fibrosis. Here, we report a novel stimulatory and synergistic effect of oncostatin M (OSM) on proinflammat...
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Full title
Synergistic induction of CCL2/MCP‐1 expression driven by oncostatin M and IL‐1β in human proximal tubular cells depends on STAT3 and p65 NFκB/RelA
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4393206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4393206
Other Identifiers
ISSN
2051-817X
E-ISSN
2051-817X
DOI
10.14814/phy2.12298
