Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
About this item
Full title
Author / Creator
Doria-Rose, Nicole A. , Schramm, Chaim A. , Gorman, Jason , Moore, Penny L. , Bhiman, Jinal N. , DeKosky, Brandon J. , Ernandes, Michael J. , Georgiev, Ivelin S. , Kim, Helen J. , Pancera, Marie , Staupe, Ryan P. , Altae-Tran, Han R. , Bailer, Robert T. , Crooks, Ema T. , Cupo, Albert , Druz, Aliaksandr , Garrett, Nigel J. , Hoi, Kam H. , Kong, Rui , Louder, Mark K. , Longo, Nancy S. , McKee, Krisha , Nonyane, Molati , O’Dell, Sijy , Roark, Ryan S. , Rudicell, Rebecca S. , Schmidt, Stephen D. , Sheward, Daniel J. , Soto, Cinque , Wibmer, Constantinos Kurt , Yang, Yongping , Zhang, Zhenhai , Mullikin, James C. , Binley, James M. , Sanders, Rogier W. , Wilson, Ian A. , Moore, John P. , Ward, Andrew B. , Georgiou, George , Williamson, Carolyn , Abdool Karim, Salim S. , Morris, Lynn , Kwong, Peter D. , Shapiro, Lawrence , Mascola, John R. , NISC Comparative Sequencing and NISC Comparative Sequencing Program
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Antibodies capable of neutralizing HIV-1 often target variable regions 1 and 2 (V1V2) of the HIV-1 envelope, but the mechanism of their elicitation has been unclear. Here we define the developmental pathway by which such antibodies are generated and acquire the requisite molecular characteristics for neutralization. Twelve somatically related neutr...
Alternative Titles
Full title
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
Authors, Artists and Contributors
Author / Creator
Schramm, Chaim A.
Gorman, Jason
Moore, Penny L.
Bhiman, Jinal N.
DeKosky, Brandon J.
Ernandes, Michael J.
Georgiev, Ivelin S.
Kim, Helen J.
Pancera, Marie
Staupe, Ryan P.
Altae-Tran, Han R.
Bailer, Robert T.
Crooks, Ema T.
Cupo, Albert
Druz, Aliaksandr
Garrett, Nigel J.
Hoi, Kam H.
Kong, Rui
Louder, Mark K.
Longo, Nancy S.
McKee, Krisha
Nonyane, Molati
O’Dell, Sijy
Roark, Ryan S.
Rudicell, Rebecca S.
Schmidt, Stephen D.
Sheward, Daniel J.
Soto, Cinque
Wibmer, Constantinos Kurt
Yang, Yongping
Zhang, Zhenhai
Mullikin, James C.
Binley, James M.
Sanders, Rogier W.
Wilson, Ian A.
Moore, John P.
Ward, Andrew B.
Georgiou, George
Williamson, Carolyn
Abdool Karim, Salim S.
Morris, Lynn
Kwong, Peter D.
Shapiro, Lawrence
Mascola, John R.
NISC Comparative Sequencing
NISC Comparative Sequencing Program
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4395007
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4395007
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13036
