In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from sponta...
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors
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Author / Creator
Barbieri, Federica , Thellung, Stefano , Ratto, Alessandra , Carra, Elisa , Marini, Valeria , Fucile, Carmen , Bajetto, Adriana , Pattarozzi, Alessandra , Würth, Roberto , Gatti, Monica , Campanella, Chiara , Vito, Guendalina , Mattioli, Francesca , Pagano, Aldo , Daga, Antonio , Ferrari, Angelo and Florio, Tullio
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Cancer stem cells (CSCs) are considered the cell subpopulation responsible for breast cancer (BC) initiation, growth, and relapse. CSCs are identified as self-renewing and tumor-initiating cells, conferring resistance to chemo- and radio-therapy to several neoplasias. Nowadays, th (about 10mM)e pharmacological targeting of CSCs is considered an ine...
Alternative Titles
Full title
In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4397725
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4397725
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-015-1235-8
