Bicarbonate Conductance and pH Regulatory Capability of Cystic Fibrosis Transmembrane Conductance Re...
Bicarbonate Conductance and pH Regulatory Capability of Cystic Fibrosis Transmembrane Conductance Regulator
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl-channel regulated by protein kinase A. The most common mutation in cystic fibrosis (CF), deletion of Phe-508 (ΔF508-CFTR), reduces Cl-secretion, but the fatal consequences of CF have been difficult to rationalize solely in terms of this defect. The aim of this study...
Alternative Titles
Full title
Bicarbonate Conductance and pH Regulatory Capability of Cystic Fibrosis Transmembrane Conductance Regulator
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_43990
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_43990
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.91.12.5340
