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Structure and function of the human calcium‐sensing receptor: insights from natural and engineered m...

Structure and function of the human calcium‐sensing receptor: insights from natural and engineered m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4401263

Structure and function of the human calcium‐sensing receptor: insights from natural and engineered mutations and allosteric modulators

About this item

Full title

Structure and function of the human calcium‐sensing receptor: insights from natural and engineered mutations and allosteric modulators

Author / Creator

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

Journal of cellular and molecular medicine, 2007-09, Vol.11 (5), p.908-922

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

• 
Introduction
• 
The CaR is a unique family 3 GPCR
• 
Architecture of the CaR
‐ 
Venus flytrap domain
‐ 
Cysteine‐rich domain
‐ 
Seven‐transmembrane domain
‐ 
Intracellular carboxyl terminus
• 
Naturally occurring inactivating mutations associated with FHH and NSHPT
• 
Naturally occurring activat...

Alternative Titles

Full title

Structure and function of the human calcium‐sensing receptor: insights from natural and engineered mutations and allosteric modulators

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4401263

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4401263

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/j.1582-4934.2007.00096.x

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