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Coupled local translation and degradation regulate growth cone collapse

Coupled local translation and degradation regulate growth cone collapse

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4408908

Coupled local translation and degradation regulate growth cone collapse

About this item

Full title

Coupled local translation and degradation regulate growth cone collapse

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-04, Vol.6 (1), p.6888-6888, Article 6888

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Local translation mediates axonal responses to Semaphorin3A (Sema3A) and other guidance cues. However, only a subset of the axonal proteome is locally synthesized, whereas most proteins are trafficked from the soma. The reason why only specific proteins are locally synthesized is unknown. Here we show that local protein synthesis and degradation ar...

Alternative Titles

Full title

Coupled local translation and degradation regulate growth cone collapse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4408908

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4408908

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms7888

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