Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's...
Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The study of late-onset/age-related Alzheimer's disease (AD)(sporadic AD, 95% of AD cases) has been hampered by a paucity of animal models. Oxidative stress is considered a causative factor in late onset/age-related AD, and aldehyde dehydrogenase 2 (ALDH2) is important for the catabolism of toxic aldehydes associated with oxidative stress. One such...
Alternative Titles
Full title
Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4409701
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4409701
Other Identifiers
ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-015-0117-y
