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SCF ubiquitin ligase-targeted therapies

SCF ubiquitin ligase-targeted therapies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4410837

SCF ubiquitin ligase-targeted therapies

About this item

Full title

SCF ubiquitin ligase-targeted therapies

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Drug discovery, 2014-12, Vol.13 (12), p.889-903

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
The ubiquitin–proteasome system (UPS) has links to numerous diseases, and the clinical success of proteasome inhibitors suggests the potential to develop drugs targeting other components of the UPS. In certain cases, the specific inhibition of individual components of the UPS may provide better therapeutic outcomes than does broad inh...

Alternative Titles

Full title

SCF ubiquitin ligase-targeted therapies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4410837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4410837

Other Identifiers

ISSN

1474-1776

E-ISSN

1474-1784

DOI

10.1038/nrd4432

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