A STIM2 splice variant negatively regulates store-operated calcium entry
A STIM2 splice variant negatively regulates store-operated calcium entry
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cellular homeostasis relies upon precise regulation of Ca
2+
concentration. Stromal interaction molecule (STIM) proteins regulate store-operated calcium entry (SOCE) by sensing Ca
2+
concentration in the ER and forming oligomers to trigger Ca
2+
entry through plasma membrane-localized Orai1 channels. Here we characterize a
STIM...
Alternative Titles
Full title
A STIM2 splice variant negatively regulates store-operated calcium entry
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4411291
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4411291
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7899