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A STIM2 splice variant negatively regulates store-operated calcium entry

A STIM2 splice variant negatively regulates store-operated calcium entry

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4411291

A STIM2 splice variant negatively regulates store-operated calcium entry

About this item

Full title

A STIM2 splice variant negatively regulates store-operated calcium entry

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-04, Vol.6 (1), p.6899-6899, Article 6899

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cellular homeostasis relies upon precise regulation of Ca
2+
concentration. Stromal interaction molecule (STIM) proteins regulate store-operated calcium entry (SOCE) by sensing Ca
2+
concentration in the ER and forming oligomers to trigger Ca
2+
entry through plasma membrane-localized Orai1 channels. Here we characterize a
STIM...

Alternative Titles

Full title

A STIM2 splice variant negatively regulates store-operated calcium entry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4411291

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4411291

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms7899

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