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SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4413894

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

About this item

Full title

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-04, Vol.5 (1), p.9841-9841, Article 9841

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Metastasis is responsible for over 90% of cancer-associated mortality. In epithelial carcinomas, a key process in metastatic progression is the epigenetic reprogramming of an epithelial-to-mesenchymal transition-like (EMT) change towards invasive cellular phenotypes. In non-epithelial cancers, different mechanisms must underlie metastatic change, b...

Alternative Titles

Full title

SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4413894

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4413894

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep09841

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