SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors
SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Metastasis is responsible for over 90% of cancer-associated mortality. In epithelial carcinomas, a key process in metastatic progression is the epigenetic reprogramming of an epithelial-to-mesenchymal transition-like (EMT) change towards invasive cellular phenotypes. In non-epithelial cancers, different mechanisms must underlie metastatic change, b...
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Full title
SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4413894
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4413894
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep09841