Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
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Author / Creator
Sandler, Netanya G. , Bosinger, Steven E. , Estes, Jacob D. , Zhu, Richard T. R. , Tharp, Gregory K. , Boritz, Eli , Levin, Doron , Wijeyesinghe, Sathi , Makamdop, Krystelle Nganou , del Prete, Gregory Q. , Hill, Brenna J. , Timmer, J. Katherina , Reiss, Emma , Yarden, Ganit , Darko, Samuel , Contijoch, Eduardo , Todd, John Paul , Silvestri, Guido , Nason, Martha , Norgren Jr, Robert B. , Keele, Brandon F. , Rao, Srinivas , Langer, Jerome A. , Lifson, Jeffrey D. , Schreiber, Gideon and Douek, Daniel C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The timing of type I interferon signalling determines the disease course of SIV infection.
Dual effect of interferon in SIV infection
Type I interferon (IFN-I) is shown here to have dual effects in rhesus macaques exposed to simian immunodeficiency virus (SIV): it is beneficial at the onset of infection but as infection progresses it becomes...
Alternative Titles
Full title
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
Authors, Artists and Contributors
Author / Creator
Bosinger, Steven E.
Estes, Jacob D.
Zhu, Richard T. R.
Tharp, Gregory K.
Boritz, Eli
Levin, Doron
Wijeyesinghe, Sathi
Makamdop, Krystelle Nganou
del Prete, Gregory Q.
Hill, Brenna J.
Timmer, J. Katherina
Reiss, Emma
Yarden, Ganit
Darko, Samuel
Contijoch, Eduardo
Todd, John Paul
Silvestri, Guido
Nason, Martha
Norgren Jr, Robert B.
Keele, Brandon F.
Rao, Srinivas
Langer, Jerome A.
Lifson, Jeffrey D.
Schreiber, Gideon
Douek, Daniel C.
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4418221
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4418221
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/nature13554