Blockade of P2X7 Receptors or Pannexin-1 Channels Similarly Attenuates Postischemic Damage
Blockade of P2X7 Receptors or Pannexin-1 Channels Similarly Attenuates Postischemic Damage
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Publisher
London, England: SAGE Publications
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Language
English
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Publisher
London, England: SAGE Publications
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Contents
The role of P2X7 receptors and pannexin-1 channels in ischemic damage remains controversial. Here, we analyzed their contribution to postanoxic depolarization after ischemia in cultured neurons and in brain slices. We observed that pharmacological blockade of P2X7 receptors or pannexin-1 channels delayed the onset of postanoxic currents and reduced...
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Full title
Blockade of P2X7 Receptors or Pannexin-1 Channels Similarly Attenuates Postischemic Damage
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4420860
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4420860
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ISSN
0271-678X
E-ISSN
1559-7016
DOI
10.1038/jcbfm.2014.262