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Evaluation of [11C]CB184 for imaging and quantification of TSPO overexpression in a rat model of her...

Evaluation of [11C]CB184 for imaging and quantification of TSPO overexpression in a rat model of her...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4424274

Evaluation of [11C]CB184 for imaging and quantification of TSPO overexpression in a rat model of herpes encephalitis

About this item

Full title

Evaluation of [11C]CB184 for imaging and quantification of TSPO overexpression in a rat model of herpes encephalitis

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European journal of nuclear medicine and molecular imaging, 2015-06, Vol.42 (7), p.1106-1118

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Evaluation of translocator protein (TSPO) overexpression is considered an attractive research tool for monitoring neuroinflammation in several neurological and psychiatric disorders. [
11
C]PK11195 PET imaging has been widely used for this purpose. However, it has a low sensitivity and a poor signal-to-noise ratio. For these reason...

Alternative Titles

Full title

Evaluation of [11C]CB184 for imaging and quantification of TSPO overexpression in a rat model of herpes encephalitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4424274

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4424274

Other Identifiers

ISSN

1619-7070

E-ISSN

1619-7089

DOI

10.1007/s00259-015-3021-x

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