Leukaemic transformation by CALM–AF10 involves upregulation of Hoxa5 by hDOT1L
Leukaemic transformation by CALM–AF10 involves upregulation of Hoxa5 by hDOT1L
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Chromosomal translocation is a common cause of leukaemia
1
and the most common chromosome translocations found in leukaemia patients involve the mixed lineage leukaemia (
MLL
) gene
2
,
3
. AF10 is one of more than 30 MLL fusion partners in leukaemia
4
. We have recently demonstrated that the H3K79 methyltransferase hD...
Alternative Titles
Full title
Leukaemic transformation by CALM–AF10 involves upregulation of Hoxa5 by hDOT1L
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4425349
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4425349
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb1464
