ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/p...
ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
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Author / Creator
Chai, Xiao , Li, Deguan , Cao, Xiaoli , Zhang, Yuchen , Mu, Juan , Lu, Wenyi , Xiao, Xia , Li, Chengcheng , Meng, Juanxia , Chen, Jie , Li, Qing , Wang, Jishi , Meng, Aimin and Zhao, Mingfeng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Iron overload, caused by hereditary hemochromatosis or repeated blood transfusions in some diseases, such as beta thalassemia, bone marrow failure and myelodysplastic syndrome, can significantly induce injured bone marrow (BM) function as well as parenchyma organ dysfunctions. However, the effect of iron overload and its mechanism remain elusive. I...
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Full title
ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4429544
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4429544
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep10181
