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UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest–Like Cells vi...

UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest–Like Cells vi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4430391

UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest–Like Cells via Suppression of Notch

About this item

Full title

UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest–Like Cells via Suppression of Notch

Publisher

United States: Elsevier Inc

Journal title

Journal of investigative dermatology, 2015-06, Vol.135 (6), p.1521-1532

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Multipotent stem cells with neural crest–like properties have been identified in the dermis of human skin. These neural crest stem cell (NCSC)–like cells display self-renewal capacity and differentiate into neural crest derivatives, including epidermal pigment–producing melanocytes. NCSC-like cells share many properties with aggressive melanoma cel...

Alternative Titles

Full title

UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest–Like Cells via Suppression of Notch

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4430391

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4430391

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2015.59

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