Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated...
Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Tau is a central player in Alzheimer's disease (AD) and related Tauopathies, where it is found as aggregates in degenerating neurons. Abnormal post-translational modifications, such as truncation, are likely involved in the pathological process. A major step forward in understanding the role of Tau truncation would be to identify the precise cleava...
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Full title
Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4431475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4431475
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep09659
