Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
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Author / Creator
Gire, Stephen K. , Goba, Augustine , Andersen, Kristian G. , Sealfon, Rachel S. G. , Park, Daniel J. , Kanneh, Lansana , Jalloh, Simbirie , Momoh, Mambu , Fullah, Mohamed , Dudas, Gytis , Wohl, Shirlee , Moses, Lina M. , Yozwiak, Nathan L. , Winnicki, Sarah , Matranga, Christian B. , Malboeuf, Christine M. , Qu, James , Gladden, Adrianne D. , Schaffner, Stephen F. , Yang, Xiao , Jiang, Pan-Pan , Nekoui, Mahan , Colubri, Andres , Coomber, Moinya Ruth , Fonnie, Mbalu , Moigboi, Alex , Gbakie, Michael , Kamara, Fatima K. , Tucker, Veronica , Konuwa, Edwin , Saffa, Sidiki , Sellu, Josephine , Jalloh, Abdul Azziz , Kovoma, Alice , Koninga, James , Mustapha, Ibrahim , Kargbo, Kandeh , Foday, Momoh , Yillah, Mohamed , Kanneh, Franklyn , Robert, Willie , Massally, James L. B. , Chapman, Sinéad B. , Bochicchio, James , Murphy, Cheryl , Nusbaum, Chad , Young, Sarah , Birren, Bruce W. , Grant, Donald S. , Scheiffelin, John S. , Lander, Eric S. , Happi, Christian , Gevao, Sahr M. , Gnirke, Andreas , Rambaut, Andrew , Garry, Robert F. , Khan, S. Humarr and Sabeti, Pardis C.
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
United States: American Association for the Advancement of Science
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More information
Scope and Contents
Contents
In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to ~2000× coverage. We observed a rapid accumulation of interhost and intrahost genetic variation, allowing us to characterize patterns of viral transmission over the init...
Alternative Titles
Full title
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Authors, Artists and Contributors
Author / Creator
Goba, Augustine
Andersen, Kristian G.
Sealfon, Rachel S. G.
Park, Daniel J.
Kanneh, Lansana
Jalloh, Simbirie
Momoh, Mambu
Fullah, Mohamed
Dudas, Gytis
Wohl, Shirlee
Moses, Lina M.
Yozwiak, Nathan L.
Winnicki, Sarah
Matranga, Christian B.
Malboeuf, Christine M.
Qu, James
Gladden, Adrianne D.
Schaffner, Stephen F.
Yang, Xiao
Jiang, Pan-Pan
Nekoui, Mahan
Colubri, Andres
Coomber, Moinya Ruth
Fonnie, Mbalu
Moigboi, Alex
Gbakie, Michael
Kamara, Fatima K.
Tucker, Veronica
Konuwa, Edwin
Saffa, Sidiki
Sellu, Josephine
Jalloh, Abdul Azziz
Kovoma, Alice
Koninga, James
Mustapha, Ibrahim
Kargbo, Kandeh
Foday, Momoh
Yillah, Mohamed
Kanneh, Franklyn
Robert, Willie
Massally, James L. B.
Chapman, Sinéad B.
Bochicchio, James
Murphy, Cheryl
Nusbaum, Chad
Young, Sarah
Birren, Bruce W.
Grant, Donald S.
Scheiffelin, John S.
Lander, Eric S.
Happi, Christian
Gevao, Sahr M.
Gnirke, Andreas
Rambaut, Andrew
Garry, Robert F.
Khan, S. Humarr
Sabeti, Pardis C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4431643
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4431643
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1259657