Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with...
Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation
About this item
Full title
Author / Creator
Montagner, Giulia , Borgatti, Monica , Altruda, Fiorella , Carandina, Gianni , Rubini, Michele , Aiello, Vincenzo , Breda, Laura , Rivella, Stefano , Gambari, Roberto , Finotti, Alessia , Cosenza, Lucia C. , Zuccato, Cristina , Fabbri, Enrica , Salvatori, Francesca , Lampronti, Ilaria , Bianchi, Nicoletta , Mancini, Irene , Breveglieri, Giulia and Fagoonee, Sharmila
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
Formats
Publication information
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Subjects
More information
Scope and Contents
Contents
Mouse models that carry mutations causing thalassemia represent a suitable tool to test in vivo new mutation-specific therapeutic approaches. Transgenic mice carrying the β-globin IVSI-6 mutation (the most frequent in Middle-Eastern regions and recurrent in Italy and Greece) are, at present, not available. We report the production and characterizat...
Alternative Titles
Full title
Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation
Authors, Artists and Contributors
Author / Creator
Borgatti, Monica
Altruda, Fiorella
Carandina, Gianni
Rubini, Michele
Aiello, Vincenzo
Breda, Laura
Rivella, Stefano
Gambari, Roberto
Finotti, Alessia
Cosenza, Lucia C.
Zuccato, Cristina
Fabbri, Enrica
Salvatori, Francesca
Lampronti, Ilaria
Bianchi, Nicoletta
Mancini, Irene
Breveglieri, Giulia
Fagoonee, Sharmila
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4434229
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4434229
Other Identifiers
ISSN
2314-6133
E-ISSN
2314-6141
DOI
10.1155/2015/687635
