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MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol...

MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4437888

MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption

About this item

Full title

MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption

Publisher

London: Nature Publishing Group UK

Journal title

Molecular psychiatry, 2015-10, Vol.20 (10), p.1240-1250

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

MicroRNAs (miRNAs) induce messenger RNA (mRNA) degradation and repress mRNA translation. Several miRNAs control the expression of the brain-derived neurotrophic factor (BDNF) in the prefrontal cortex (PFC). The BDNF signaling pathway is activated by moderate intake of alcohol to prevent escalation to excessive drinking. Here, we present data to sug...

Alternative Titles

Full title

MicroRNA-30a-5p in the prefrontal cortex controls the transition from moderate to excessive alcohol consumption

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4437888

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4437888

Other Identifiers

ISSN

1359-4184

E-ISSN

1476-5578

DOI

10.1038/mp.2014.120

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