Major histocompatibility complex associations of ankylosing spondylitis are complex and involve furt...
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
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Author / Creator
Cortes, Adrian , Pulit, Sara L. , Leo, Paul J. , Pointon, Jenny J. , Robinson, Philip C. , Weisman, Michael H. , Ward, Michael , Gensler, Lianne S. , Zhou, Xiaodong , Garchon, Henri-Jean , Chiocchia, Gilles , Nossent, Johannes , Lie, Benedicte A. , Førre, Øystein , Tuomilehto, Jaakko , Laiho, Kari , Bradbury, Linda A. , Elewaut, Dirk , Burgos-Vargas, Ruben , Stebbings, Simon , Appleton, Louise , Farrah, Claire , Lau, Jonathan , Haroon, Nigil , Mulero, Juan , Blanco, Francisco J. , Gonzalez-Gay, Miguel A. , Lopez-Larrea, C , Bowness, Paul , Gaffney, Karl , Gaston, Hill , Gladman, Dafna D. , Rahman, Proton , Maksymowych, Walter P. , Crusius, J. Bart A. , van der Horst-Bruinsma, Irene E. , Valle-Oñate, Raphael , Romero-Sánchez, Consuelo , Hansen, Inger Myrnes , Pimentel-Santos, Fernando M. , Inman, Robert D. , Martin, Javier , Breban, Maxime , Wordsworth, Bryan Paul , Reveille, John D. , Evans, David M. , de Bakker, Paul I.W. and Brown, Matthew A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which
HLA-B*27
is the major genetic risk factor, although its role in the aetiology of AS remains elusive. To better understand the genetic basis of the MHC susceptibility loci, we genotyped 7,264 MHC SNPs in 22,647 AS cases and controls of European descent....
Alternative Titles
Full title
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1
Authors, Artists and Contributors
Author / Creator
Pulit, Sara L.
Leo, Paul J.
Pointon, Jenny J.
Robinson, Philip C.
Weisman, Michael H.
Ward, Michael
Gensler, Lianne S.
Zhou, Xiaodong
Garchon, Henri-Jean
Chiocchia, Gilles
Nossent, Johannes
Lie, Benedicte A.
Førre, Øystein
Tuomilehto, Jaakko
Laiho, Kari
Bradbury, Linda A.
Elewaut, Dirk
Burgos-Vargas, Ruben
Stebbings, Simon
Appleton, Louise
Farrah, Claire
Lau, Jonathan
Haroon, Nigil
Mulero, Juan
Blanco, Francisco J.
Gonzalez-Gay, Miguel A.
Lopez-Larrea, C
Bowness, Paul
Gaffney, Karl
Gaston, Hill
Gladman, Dafna D.
Rahman, Proton
Maksymowych, Walter P.
Crusius, J. Bart A.
van der Horst-Bruinsma, Irene E.
Valle-Oñate, Raphael
Romero-Sánchez, Consuelo
Hansen, Inger Myrnes
Pimentel-Santos, Fernando M.
Inman, Robert D.
Martin, Javier
Breban, Maxime
Wordsworth, Bryan Paul
Reveille, John D.
Evans, David M.
de Bakker, Paul I.W.
Brown, Matthew A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443427
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443427
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms8146