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Major histocompatibility complex associations of ankylosing spondylitis are complex and involve furt...

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve furt...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443427

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which
HLA-B*27
is the major genetic risk factor, although its role in the aetiology of AS remains elusive. To better understand the genetic basis of the MHC susceptibility loci, we genotyped 7,264 MHC SNPs in 22,647 AS cases and controls of European descent....

Alternative Titles

Full title

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443427

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443427

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms8146

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