Bispecific T‐cell engagers for cancer immunotherapy
Bispecific T‐cell engagers for cancer immunotherapy
About this item
Full title
Author / Creator
Publisher
United States: Nature Publishing Group
Journal title
Language
English
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Publisher
United States: Nature Publishing Group
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Scope and Contents
Contents
Bispecific T‐cell engagers (BiTEs) are a new class of immunotherapeutic molecules intended for the treatment of cancer. These molecules enhance the patient's immune response to tumors by retargeting T cells to tumor cells. BiTEs are constructed of two single‐chain variable fragments (scFv) connected in tandem by a flexible linker. One scFv binds to...
Alternative Titles
Full title
Bispecific T‐cell engagers for cancer immunotherapy
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4445461
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4445461
Other Identifiers
ISSN
0818-9641
E-ISSN
1440-1711
DOI
10.1038/icb.2014.93
