Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Cisca Wijmenga and colleagues report fine mapping of the association signal in the MHC region in individuals with celiac disease. They identify five additional risk factors that are independent of HLA-DQ alleles and that account for 18% of the genetic risk for this disease.
Although dietary gluten is the trigger for celiac disease, risk is stron...
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Full title
Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4449296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4449296
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3268
