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p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less...

p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4454132

p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo

About this item

Full title

p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo

Publisher

London, England: Libertas Academica

Journal title

Gene Regulation and Systems Biology, 2015-01, Vol.2015 (9), p.1-14

Language

English

Formats

Publication information

Publisher

London, England: Libertas Academica

More information

Scope and Contents

Contents

The goal of the present study was to compare hepatic toxicogenomic signatures across in vitro and in vivo mouse models following exposure to acetaminophen (APAP) or its relatively nontoxic regioisomer 3′-hydroxyacetanilide (AMAP). Two different Affymetrix microarray platforms and one Agilent Oligonucleotide microarray were utilized. APAP and AMAP t...

Alternative Titles

Full title

p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4454132

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4454132

Other Identifiers

ISSN

1177-6250

E-ISSN

1177-6250

DOI

10.4137/GRSB.S25388

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