Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing...
Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages
About this item
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Author / Creator
Kumar, S , Torres, M P , Kaur, S , Rachagani, S , Joshi, S , Johansson, S L , Momi, N , Baine, M J , Gilling, C E , Smith, L M , Wyatt, T A , Jain, M , Joshi, S S and Batra, S K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Smoking is an established risk factor for pancreatic cancer (PC), but late diagnosis limits the evaluation of its mechanistic role in the progression of PC. We used a well-established genetically engineered mouse model (LSL-K-ras
G12D
) of PC to elucidate the role of smoking during initiation and development of pancreatic intraepithelial neop...
Alternative Titles
Full title
Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4457293
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4457293
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2014.154
