Regulation of age-related macular degeneration-like pathology by complement factor H
Regulation of age-related macular degeneration-like pathology by complement factor H
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Significance Age-related macular degeneration (AMD) affects approximately one-third of Americans over 70 and is characterized by lipoprotein-rich sub-retinal pigmented epithelium (sub-RPE) deposits. Substantial evidence has emerged that implicates complement factor H (CFH) in the pathogenesis of AMD. Here, we conduct an in vivo analysis to elucidat...
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Full title
Regulation of age-related macular degeneration-like pathology by complement factor H
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4466717
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4466717
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1424391112
