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Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4468845

Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

About this item

Full title

Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-06, Vol.6 (1), p.7396, Article 7396

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ras (Rat sarcoma) protein is a central regulator of cell growth and proliferation. Mutations in the
RAS
gene are known to occur in human cancers and have been shown to contribute to carcinogenesis. In this study, we show that the multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin-effector domain DUF5
Vv
from
Vibrio vulnifi...

Alternative Titles

Full title

Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4468845

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4468845

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms8396

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