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Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminop...

Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminop...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4469719

Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts

About this item

Full title

Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts

Publisher

New York: Springer US

Journal title

Journal of medical toxicology, 2015-06, Vol.11 (2), p.218-222

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Introduction
Acetaminophen-cysteine adducts (APAP-CYS) are a serum biomarker of acetaminophen exposure, formed when the oxidative metabolite of acetaminophen binds to cysteine residues of hepatic proteins. APAP-CYS adducts become elevated in cases of acute liver failure following acetaminophen overdose and have been proposed as a diagnostic tool...

Alternative Titles

Full title

Confirming the Causative Role of Acetaminophen in Indeterminate Acute Liver Failure Using Acetaminophen-Cysteine Adducts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4469719

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4469719

Other Identifiers

ISSN

1556-9039

E-ISSN

1937-6995

DOI

10.1007/s13181-015-0476-x

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