The RNA-binding protein HuR is essential for the B cell antibody response
The RNA-binding protein HuR is essential for the B cell antibody response
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Author / Creator
Diaz-Muñoz, Manuel D , Bell, Sarah E , Fairfax, Kirsten , Monzon-Casanova, Elisa , Cunningham, Adam F , Gonzalez-Porta, Mar , Andrews, Simon R , Bunik, Victoria I , Zarnack, Kathi , Curk, Tomaž , Heggermont, Ward A , Heymans, Stephane , Gibson, Gary E , Kontoyiannis, Dimitris L , Ule, Jernej and Turner, Martin
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The RNA-binding protein HuR post-transcriptionally regulates mRNA splicing. Turner and colleagues demonstrate that HuR serves a critical role in thymus-independent antigen responses by regulating the fate of genes related to B cell energy use.
Post-transcriptional regulation of mRNA by the RNA-binding protein HuR (encoded by
Elavl1
) is re...
Alternative Titles
Full title
The RNA-binding protein HuR is essential for the B cell antibody response
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4479220
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4479220
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3115