New PARP targets for cancer therapy
New PARP targets for cancer therapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The poly(ADP-ribose) polymerase (PARP) family comprises 17 enzymes, which generate poly(ADP-ribose) and/or mono(ADP-ribose) (MAR) that can modify target protein function and can function as a signalling scaffold. These modifications may have various roles in cancer and, as discussed in this Opinion article, inhibitors of MARylation in particular ma...
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Full title
New PARP targets for cancer therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4480224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4480224
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3748
