Disruption of DNA-methylation-dependent long gene repression in Rett syndrome
Disruption of DNA-methylation-dependent long gene repression in Rett syndrome
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Rett syndrome is caused by mutation of the
MECP2
gene that codes for a protein that binds methylated DNA; this study reveals that MeCP2 affects the expression of long genes, which often serve neuronal functions.
Role of MECP2 in Rett syndrome
Autism-related Rett syndrome is caused by disruption of the
MECP2
gene, which codes for a...
Alternative Titles
Full title
Disruption of DNA-methylation-dependent long gene repression in Rett syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4480648
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4480648
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14319
