β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation
β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The mechanisms through which β-amyloid impairs human memory remain unclear. This study shows that regional-specific β-amyloid load in cognitively normal older adults impairs NREM slow wave oscillations, thereby compromising overnight hippocampus-dependent memory consolidation. NREM sleep disruption therefore represents a novel mechanistic pathway t...
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Full title
β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4482795
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4482795
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.4035
