Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer...
Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment
About this item
Full title
Author / Creator
Zhu, Xi , Yingjie Xu , Luisa M. Solis , Wei Tao , Liangzhe Wang , Carmen Behrens , Xiaoyang Xu , Lili Zhao , Danny Liu , Jun Wu , Ning Zhang , Ignacio I. Wistuba , Omid C. Farokhzad , Bruce R. Zetter and Jinjun Shi
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
RNA interference (RNAi) represents a promising strategy for identification and validation of putative therapeutic targets and for treatment of a myriad of important human diseases including cancer. However, the effective systemic in vivo delivery of small interfering RNA (siRNA) to tumors remains a formidable challenge. Using a robust self-assembly...
Alternative Titles
Full title
Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4485147
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4485147
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1505629112
