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Cohesin-mediated interactions organize chromosomal domain architecture

Cohesin-mediated interactions organize chromosomal domain architecture

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4489921

Cohesin-mediated interactions organize chromosomal domain architecture

About this item

Full title

Cohesin-mediated interactions organize chromosomal domain architecture

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2013-12, Vol.32 (24), p.3119-3129

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

To ensure proper gene regulation within constrained nuclear space, chromosomes facilitate access to transcribed regions, while compactly packaging all other information. Recent studies revealed that chromosomes are organized into megabase‐scale domains that demarcate active and inactive genetic elements, suggesting that compartmentalization is impo...

Alternative Titles

Full title

Cohesin-mediated interactions organize chromosomal domain architecture

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4489921

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4489921

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2013.237

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