Detection of BCR-ABL T315I mutation by peptide nucleic acid directed PCR clamping and by peptide nuc...
Detection of BCR-ABL T315I mutation by peptide nucleic acid directed PCR clamping and by peptide nucleic acid FISH
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Author / Creator
Rosso, Valentina , Bracco, Enrico , Pedrola, Roberto , Carturan, Sonia , Signorino, Elisabetta , Petiti, Jessica , Calabrese, Chiara , Nicoli, Paolo , De Gobbi, Marco , Gaidano, Valentina , Gallo, Daniela , Ulisciani, Stefano , Fava, Carmen , Rege-Cambrin, Giovanna , Frassoni, Francesco , Saglio, Giuseppe and Cilloni, Daniela
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Mutations of the BCR-ABL1 fusion gene represent a well established cause of resistance to tyrosine kinase inhibitors. Among the different mutations identified T315I is of particular concern since it is not effectively targeted by the majority of Tyrosine Kinase Inhibitors so far available. We developed a novel assay based on peptide nucleic acid (P...
Alternative Titles
Full title
Detection of BCR-ABL T315I mutation by peptide nucleic acid directed PCR clamping and by peptide nucleic acid FISH
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4490729
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4490729
Other Identifiers
ISSN
2050-7771
E-ISSN
2050-7771
DOI
10.1186/s40364-015-0039-y
