Structural basis of blocking integrin activation and deactivation for anti-inflammation
Structural basis of blocking integrin activation and deactivation for anti-inflammation
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Integrins mediate leukocyte accumulation to the sites of inflammation, thereby enhancing their potential as an important therapeutic target for inflammatory disorders. Integrin activation triggered by inflammatory mediators or signaling pathway is a key step to initiate leukocyte migration to inflamed tissues; however, an appropriately regulated in...
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Full title
Structural basis of blocking integrin activation and deactivation for anti-inflammation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4495637
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4495637
Other Identifiers
ISSN
1423-0127,1021-7770
E-ISSN
1423-0127
DOI
10.1186/s12929-015-0159-6
