PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood...
PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Cord blood hematopoietic stem cells (CB-HSCs) are an outstanding source for transplantation approaches. However, the amount of cells per donor is limited and culture expansion of CB-HSCs is accompanied by a loss of engraftment potential. In order to analyze the molecular mechanisms leading to this impaired potential we profiled global and local epi...
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PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4510577
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4510577
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep12319
