Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain
Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain
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Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
The brain has a limited capacity to self-protect against protein aggregate-associated pathology, and mounting evidence supports a role for phagocytic glia in this process. We have established a
Drosophila
model to investigate the role of phagocytic glia in clearance of neuronal mutant huntingtin (Htt) aggregates associated with Huntington dis...
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Full title
Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4515032
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4515032
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7768
