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Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-s...

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4523390

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

About this item

Full title

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-04, Vol.6 (1), p.6855-6855, Article 6855

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Auditory sensory hair cells depend on stereocilia with precisely regulated lengths to detect sound. Since stereocilia are primarily composed of crosslinked, parallel actin filaments, regulated actin dynamics are essential for controlling stereocilia length. Here we assessed stereocilia actin turnover by monitoring incorporation of inducibly express...

Alternative Titles

Full title

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4523390

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4523390

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms7855

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