Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid met...
Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E−/− mice by activating autophagy
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Author / Creator
WANG, JIA , WU, JIE , WU, HONG , LIU, XINGZHEN , CHEN, YINGJIAN , WU, JIANYING , HU, CHENGJIN and ZOU, DAJIN
Publisher
Greece: D.A. Spandidos
Journal title
Language
English
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Publication information
Publisher
Greece: D.A. Spandidos
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Scope and Contents
Contents
The aim of the present study was to determine whether liraglutide (LRG), a long acting glucagon-like peptide 1 analogue, exerted a protective effect on free fatty acid (FFA)-treated pancreatic β-cells via activating autophagy. INS-1 insulinoma pancreatic islet cell lines were treated with FFA and the levels of cell necrosis, apoptosis and autophagy...
Alternative Titles
Full title
Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E−/− mice by activating autophagy
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4526029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4526029
Other Identifiers
ISSN
1791-2997
E-ISSN
1791-3004
DOI
10.3892/mmr.2015.3944
