Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
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Author / Creator
Ran, Jie , Yang, Yunfan , Li, Dengwen , Liu, Min and Zhou, Jun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cilia play important roles in sensing extracellular signals and directing fluid flow. Ciliary dysfunction is associated with a variety of diseases known as ciliopathies. Histone deacetylase 6 (HDAC6) has recently emerged as a major driver of ciliary disassembly, but little is known about the downstream players. Here we provide the first evidence th...
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Full title
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4526867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4526867
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep12917
