An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatoc...
An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells
About this item
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Author / Creator
Qian, Hui , Deng, Xing , Huang, Zhao-Wei , Wei, Ji , Ding, Chen-Hong , Feng, Ren-Xin , Zeng, Xin , Chen, Yue-Xiang , Ding, Jin , Qiu, Lei , Hu, Zhen-Lin , Zhang, Xin , Wang, Hong-Yang , Zhang, Jun-Ping and Xie, Wei-Fen
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hepatocytes are critical for the maintenance of liver homeostasis, but its involvement in hepatic fibrogenesis remains elusive. Hepatocyte nuclear factor 1α (HNF1α) is a liver-enriched transcription factor that plays a key role in hepatocyte function. Our previous study revealed a significant inhibitory effect of HNF1α on hepatocellular carcinoma....
Alternative Titles
Full title
An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528057
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528057
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2015.84
