KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute l...
KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
High hyperdiploidy defines the largest genetic entity of childhood acute lymphoblastic leukemia (ALL). Despite its relatively low recurrence risk, this subgroup generates a high proportion of relapses. The cause and origin of these relapses remains obscure. We therefore explored the mutational landscape in high hyperdiploid (HD) ALL with whole-exom...
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KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4530204
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4530204
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2015.107
