Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis...
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice
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Author / Creator
Guida, F , Luongo, L , Marmo, F , Romano, R , Iannotta, M , Napolitano, F , Belardo, C , Marabese, I , D'Aniello, A , De Gregorio, D , Rossi, F , Piscitelli, F , Lattanzi, R , de Bartolomeis, A , Usiello, A , Di Marzo, V , de Novellis, V and Maione, S
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Enhanced supraspinal glutamate levels following nerve injury are associated with pathophysiological mechanisms responsible for neuropathic pain. Chronic pain can interfere with specific brain areas involved in glutamate-dependent neuropsychological processes, such as cognition, memory, and decision-making. The medial prefrontal cortex (mPFC) is tho...
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Full title
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4532244
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4532244
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ISSN
1756-6606
E-ISSN
1756-6606
DOI
10.1186/s13041-015-0139-5
